21
2
1777
Cat. No. | Product Name | Target | Signaling Pathways |
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T78707 | IL-1β-IN-2 | ||
IL-1β-IN-2为大麻酚衍生物,该化合物作为IL-1β抑制剂表现出优良效力,兼具抗炎及镇痛特性。 | |||
T74819 |
IL-1β-IN-1
|
||
IL-1β-IN-1 是一种大麻二酚衍生物,是一种有效的 IL-1β抑制剂。IL-1β-IN-1 具有抗炎和镇痛作用。 | |||
T9656 |
AP-1/NF-κB activation inhibitor 1
|
NF-κB; DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; NF-κB |
AP-1/NF-κB activation inhibitor 1 是一种有效的 AP-1和 NF-κB 介导的转录激活抑制剂(IC50=1 μM),不阻断 β-actin 启动子驱动的基础转录。AP-1/NF-κB activation inhibitor 1 对受刺激细胞中 IL-2和 IL-8的产生水平有相似的抑制作用。 | |||
T0097 |
MRT67307
MRT67307 HCl |
IκB/IKK; Autophagy | Autophagy; NF-κB |
MRT67307 是一种IKKε和TBK-1的双抑制剂,IC50分别为 160 和 19 nM。它抑制细胞自噬,也可抑制ULK1和ULK2,IC50分别为 45 和 38 nM。 | |||
T68721 |
Cantharidin imide
|
||
Cantharidin imide is a PP1/2A inhibitor found in Canarthis vesicatoria. It inhibits proliferation of colorectal cancer cells, increases MCP-1, IL-6, and IL-β levels, and inhibits differentiation and resorptive activity of osteoclasts. This compound can produce severe skin inflammation, and is extremely toxic if ingested orally. | |||
T71884 |
ß-Carboline-1-carboxylic acid
|
||
β-Carboline-1-carboxylic acid is an alkaloid that has been found in P. quassioides and has diverse biological activities. It reduces LPS-induced increases in MCP-1, TNF-α, IL-6, and IL-1β levels in RAW 264.7 cells when used at a concentration of 15 µg/ml and inhibits the epithelial-to-mesenchymal transition (EMT) induced by TGF-β1 in A549 cells. β-Carboline-1-carboxylic acid induces cytotoxicity in CT26.WT, K562, and SGC-7901 cells (IC50s = 14.96, 22.11, and 19.7 µg/ml, respectively) but not Hep... | |||
T29542 |
AC708
AC 708,AC-708 |
||
AC708 is a small molecule CSF1R inhibitor that effectively inhibits CSF1R phosphorylation mediated by CSF-1 (IC50 = 26 nM) and IL-34 (IC50 = 33 nM). It also inhibited the activity of growth factor-dependent cells cultured in CSF-1 (IC50 = 38 nM) or IL-34 | |||
T75096 | STING agonist-28 | ||
STINGagonist-28 (CF510) 是一种非核苷酸小分子STING 激动剂。STINGagonist-23 激活STING,增加STING、TBK1和IRF3的磷酸化。STINGagonist-23 可促进肿瘤细胞中IFN-β、IL-6、CXCL-10、TNF-α、ISG-15和CCL-5的水平。STINGagonist-23 表现出抗SARS-CoV 系列的活性。 | |||
T75094 | STING agonist-26 | ||
STINGagonist-26 (CF508) 是一种非核苷酸小分子STING 激动剂。STINGagonist-23 激活STING,增加STING、TBK1和IRF3的磷酸化。STINGagonist-23 可促进肿瘤细胞中IFN-β、IL-6、CXCL-10、TNF-α、ISG-15和CCL-5的水平。STINGagonist-23 表现出抗SARS-CoV 系列的活性。 | |||
T75092 | STING agonist-24 | ||
STINGagonist-24 (CF504) 是一种非核苷酸小分子STING 激动剂。STINGagonist-23 激活STING,增加STING、TBK1和IRF3的磷酸化。STINGagonist-23 可促进肿瘤细胞中IFN-β、IL-6、CXCL-10、TNF-α、ISG-15和CCL-5的水平。STINGagonist-23 表现出抗SARS-CoV 系列的活性。 | |||
T68321 |
AS1940477
|
||
AS1940477 is p38 MAPK inhibitor. AS1940477 inhibited the enzymatic activity of recombinant p38α and β isoforms but showed no effect against other 100 protein kinases including p38γ and δ isoforms. In human peripheral blood mononuclear cells, AS1940477 inhibited lipopolysaccharide (LPS)- or phytohemagglutinin A (PHA)-induced production of proinflammatory cytokines, including TNFα, IL-1β, and IL-6 at low concentrations (LPS/TNFα, IC(50)=0.45n M; PHA/TNFα, IC(50)=0.40 nM). In addition, equivalent c... | |||
T75093 | STING agonist-25 | ||
STINGagonist-25 (CF505) 是一种非核苷酸小分子 STING 激动剂。STINGagonist-23 激活 STING,增加 STING、TBK1和 IRF3的磷酸化。STINGagonist-23 可促进肿瘤细胞中IFN-β、IL-6、CXCL-10、TNF-α、ISG-15和CCL-5的水平。STINGagonist-23 表现出抗SARS-CoV 系列的活性。 | |||
T36408 |
Rhein-13C4
Rhein-13C4 |
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Rhein-13C4 is intended for use as an internal standard for the quantification of rhein by GC- or LC-MS. Rhein is an anti-inflammatory anthraquinone found in rhubarb and is the bioactive derivative of its prodrug diacerein . At 10 μM, rhein inhibits IL-1β signaling, suppressing signaling through NF-κB, and reduces the expression of the matrix metalloproteases MMP-1 and MMP-13.1 It inhibits IKKβ (IC50 = 11.8 μM), decreasing iNOS and IL-6 expression in LPS-stimulated macrophages but paradoxically i... | |||
T75091 | STING agonist-23 | ||
STINGagonist-23 (CF502) 是一种非核苷酸小分子 STING 激动剂。STINGagonist-23 激活 STING,增加 STING、TBK1和 IRF3的磷酸化。STINGagonist-23 可促进肿瘤细胞中 IFN-β、IL-6、CXCL-10、TNF-α、ISG-15和 CCL-5的水平。STINGagonist-23 表现出抗 SARS-CoV 系列的活性。 | |||
T38161 |
STING Agonist C11
STING Agonist C11 |
||
STING agonist C11 is an agonist of the stimulator of interferon genes (STING) pathway.1 It induces secretion of type I IFN from THF and MM6 cells when used at a concentration of 50 μM. STING agonist C11 induces phosphorylation of IFN regulatory factor 3 (IRF3) and increases expression of IFIT1 and viperin, but not IL-1β, IL-6, or IL-8 in THF cells in a STING-dependent manner. It reduces viral titers of chikungunya, Venezuelan equine encephalitis, o'nyong-nyong, Mayaro, and Ross River viruses gro... | |||
T38160 |
STING Agonist 1a
|
||
STING agonist 1a is an agonist of stimulator of interferon genes (STING).1It induces expression of an IRF-inducible SEAP reporter gene in a cell-based assay (EC50= 16.77 μM). STING agonist 1a (12.5-100 μM) induces expression of IFN-β, IL-6, and chemokine (C-X-C motif) ligand 10 (CXCL10) in THP-1 cells, an effect that can be reversed by STING knockout or the STING inhibitor H-151 . 1.Hou, H., Yang, R., Liu, X., et al.Discovery of triazoloquinoxaline as novel STING agonists via structure-based vir... | |||
T35451 |
β-Defensin-2 (human) (trifluoroacetate salt)
|
||
β-Defensin-2 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts.1It inhibits the growth of periodontopathogenic and cariogenic bacteria, includingP. gingivalisandS. salivarius.2β-Defensin-2 (30 μg/ml) stimulates gene expression and production of IL-6, IL-10, CXCL10, CCL2, MIP-3α, and RANTES by keratinocytes.3It also stimulates calcium mobilization, migration, and proliferation of keratinocytes whe... | |||
T37449 |
SR 12460
|
||
SR 12460 is a mimetic of the IκB kinase β (IKKβ) NEMO/IKKγ-binding domain (NBD) that inhibits the protein-protein interaction between the IKK complex subunits NF-κB essential modulator (NEMO/IKKγ) and IKKβ.1It inhibits TNF-α-induced NF-κB activation in a reporter assay when used at concentrations ranging from 25 to 150 μM. It reduces LPS-induced production of IL-6 in RAW 264.7 cells. SR 12460 (30 mg/kg) improves grip strength in themdxmouse model of Duchenne muscular dystrophy. 1.Zhao, J., Zhang... | |||
T83779 |
EP4 Antagonist 14
Prostaglandin E2 Receptor 4 Antagonist 14,PGE2 Receptor 4 Antagonist 14 |
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EP4 antagonist 14是一种前列腺素E2(PGE2)受体亚型EP4的拮抗剂,其在使用表达人源受体的HEK293细胞的报告基因测定中的IC50值为1.1 nM。它还能抑制PGE2诱导的同种细胞中的β-阿雷斯汀招募(IC50 = 0.9 nM)。EP4 antagonist 14(10 µM)能减少RAW 264.7巨噬细胞中PGE2诱导的mRNA表达,这些mRNA编码Il-4、巨噬细胞甘露糖受体1(Mrc1)、几丁质酶样蛋白3(Chil3)、趋化因子(C-X-C)基序配体1(Cxcl1)、表达在髓样细胞上的触发受体2(Trem2)和精氨酸酶-1(Arg1)。在体内,EP4 antagonist 14(每天30 mg/kg),结合抗PD-1抗体,能够在CT26小鼠结肠癌模型中抑制肿瘤生长并增加CD8+ T细胞对肿瘤的浸润。 | |||
T35864 |
T-5342126
|
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T-5342126 is a toll-like receptor 4 (TLR4) antagonist.1It reduces LPS-induced production of nitric oxide (NO) in RAW 264.7 cells (IC50= 27.8 μM), as well as decreases LPS-induced IL-8, TNF-α, and IL-6 production in isolated human whole blood (IC50s = 110.5, 315.6, and 318.4 μM, respectively). T-5342126 (82 mg/kg) reduces ethanol intake and the abundance of ionized calcium-binding adapter molecule 1 (Iba1), a marker of microglial activation, in the central nucleus of the amygdala in ethanol-depen... | |||
T36461 |
CAY10748
CAY10748 |
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CAY10748 is an agonist of stimulator of interferon genes (STING; IC50= 0.3794 μM in a competition binding assay).1It activates STING in STING-expressing, but not STING knockout, THP-1 cells (EC50s = 0.287 and >100 μM, respectively, in a reporter assay). It induces phosphorylation of STING at the serine in position 366, as well as phosphorylation of TBK1 and IFN regulatory factor 3 (IRF3), indicating activation of the STING-TBK1-IRF3 signaling pathway. CAY10748 increases the secretion of IFN-β an... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3887 |
Rosarin
|
Others | Others |
Rosarin 是从玫瑰红景天中分离出来的肉桂醇糖苷。它抑制小鼠肾脏和大脑前额皮层中促炎因子 iNOS,IL-1β 和 TNF-α 的表达。它具有抗炎和神经保护作用。 | |||
T4115 |
Auraptene
橙皮油内酯,7-geranyloxycoumarin,橙皮油素 |
MMP; BACE | Neuroscience; Proteases/Proteasome |
Auraptene 是一种丰富的天然香叶氧基香豆素。它能够抑制基质金属蛋白酶 2 以及关键炎症因子,包括 IL-6,IL-8 和趋化因子 (C-C 基序) 配体-5 (CCL5)的分泌。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01999 |
IL-1 beta/IL-1F2 Protein, Human, Recombinant (His)
IL-1,IL1-β,白介素,... |
Human | E. coli |
IL-1 beta/IL-1F2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 32.3 kDa and the accession number is P01584. | |||
TMPY-01049 |
IL-1 beta/IL-1F2 Protein, Human, Recombinant
IL-1 beta,interleukin 1, beta, |
Human | E. coli |
IL-1 beta/IL-1F2 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17 kDa and the accession number is P01584. | |||
TMPY-02134 |
IL-1 beta/IL-1F2 Protein, Mouse, Recombinant
Il-1b,IL-1beta,白细胞介素,int... |
Mouse | E. coli |
IL-1 beta/IL-1F2 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.5 kDa and the accession number is P10749. | |||
TMPY-02568 |
IL-1 beta/IL-1F2 Protein, Canine, Recombinant
interleukin 1, beta,IL-1 β |
Canine | E. coli |
IL-1 beta/IL-1F2 Protein, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.6 kDa and the accession number is Q28292. | |||
TMPY-02445 |
IL-1 beta/IL-1F2 Protein, Rhesus, Recombinant
interleukin 1, beta,IL-1 β |
Rhesus | E. coli |
IL-1 beta/IL-1F2 Protein, Rhesus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.5 kDa and the accession number is P48090. | |||
TMPY-02227 |
IL-1 beta/IL-1F2 Protein, Rat, Recombinant (mature form)
白细胞介素,interleukin 1, beta,白介素,interleukin 1 |
Rat | E. coli |
IL-1 beta/IL-1F2 Protein, Rat, Recombinant (mature form) is expressed in E. coli expression system. The predicted molecular weight is 17.4 kDa and the accession number is Q63264-1. | |||
TMPK-00515 |
IL-1 beta/IL-1F2 Protein, Cynomolgus, Recombinant (His)
Interleukin-1 β,IL-1 bet... |
Cynomolgus | E. coli |
Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after inflammasome-mediated activation. IL-1 signaling activates innate immune cells including antigen presenting cells, and drives polarization of CD4 T cells towards T helper type (Th) 1 and Th17 cells. IL-1 beta/IL-1F2 Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expression system with C-His tag. The p... | |||
TMPK-00161 |
IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi)
Interleukin-1 beta,IL-1 β |
Human | E. coli |
Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after inflammasome-mediated activation. IL-1 signaling activates innate immune cells including antigen presenting cells, and drives polarization of CD4 T cells towards T helper type (Th) 1 and Th17 cells. IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi) is expressed in E. coli expression system with C-His-Avi tag. ... | |||
TMPK-00162 |
IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi), Biotinylated
IL-1 β,IL-1... |
Human | E. coli |
Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after inflammasome-mediated activation. IL-1 signaling activates innate immune cells including antigen presenting cells, and drives polarization of CD4 T cells towards T helper type (Th) 1 and Th17 cells. IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with C... | |||
TMPY-01701 |
IL-12RB1 Protein, Human, Recombinant (His)
interleukin 12 receptor, β1,I... |
Human | HEK293 Cells |
IL-12RB1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.5 kDa and the accession number is P42701-1. | |||
TMPJ-01392 |
IL-1 beta/IL-1F2 Protein, Cavia porcellus, Recombinant (His)
IL-1 β,IL1B, |
Cavia porcellus | E. coli |
Interleukin-1 beta (IL1B) belongs to the IL-1 family. Interleukin 1 (IL-1) is a family of polypeptide cytokines consisting of two agonists, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2) encoded by two distinct genes and perform identical biological functions. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response. It is identified as endogenous pyrogens, and... | |||
TMPY-01886 |
IL-1 beta/IL-1F2 Protein, Rat, Recombinant (His)
IL-1 β,interleukin 1, |
Rat | E. coli |
IL-1 beta/IL-1F2 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 32.1 kDa and the accession number is Q63264-1. | |||
TMPY-00612 |
IL-1 beta/IL-1F2 Protein, Sus scrofa (Pig), Recombinant
interleukin 1, β,IL-1 |
Sus scrofa (Pig) | E. coli |
IL-1 beta/IL-1F2 Protein, Sus scrofa (Pig), Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.7 kDa and the accession number is P26889. | |||
TMPY-02397 |
IL-1 beta/IL-1F2 Protein, Feline, Recombinant
interleukin 1, beta,白细胞介素,白介素,interleukin 1 |
Feline | E. coli |
IL-1 beta/IL-1F2 Protein, Feline, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.5 kDa and the accession number is P41687. | |||
TMPY-04011 |
IL-1 beta/IL-1F2 Protein, Rabbit, Recombinant
白介素,IL1-β,interleukin 1,... |
Rabbit | E. coli |
IL-1 beta/IL-1F2 Protein, Rabbit, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.5 kDa and the accession number is P14628. | |||
TMPK-00493 |
OSMR Protein, Cynomolgus, Recombinant (His)
OSMR,IL-31R-β,PLCA1,... |
Cynomolgus | HEK293 Cells |
OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and promotes mitochondrial respiration. Deletion of OSMR impairs spare respiratory capacity, increases reactive oxygen species, and sensitizes BTSCs to IR-induced cell death. OSMR Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted ... | |||
TMPK-00571 |
OSMR Protein, Canine, Recombinant (His)
OSMRB,IL-31R-β,OSMR,OSMRBMGC1... |
Canine | HEK293 Cells |
OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and promotes mitochondrial respiration. Deletion of OSMR impairs spare respiratory capacity, increases reactive oxygen species, and sensitizes BTSCs to IR-induced cell death. OSMR Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted mole... | |||
TMPJ-00363 |
IL-12RB1 Protein, Human, Recombinant (hFc)
IL-12R-β1,IL- |
Human | HEK293 Cells |
Interleukin12 receptor subunit beta 1 (IL12RB1) is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. IL12RB1 can spontaneously form homodimers and -oligomers, which are able to bind IL12 with only low affinity. IL12 high affinity receptor complex is composed of two subunits designated IL12RB1 and IL12RB2. While IL12RB1 interacts with the IL-12p40 subunit, IL-12p35 is mainly connecting with IL12RB2. This receptor chain is also responsible for transmitting the IL... | |||
TMPY-00854 |
IL-1 alpha/IL-1A Protein, Human, Recombinant
IL-1F1,interleukin 1, α,... |
Human | HEK293 Cells |
IL-1 alpha/IL-1A Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 18 kDa and the accession number is P01583. | |||
TMPY-01738 |
IL-1 alpha/IL-1A Protein, Mouse, Recombinant
interleukin 1, α,IL-1 α/IL |
Mouse | E. coli |
IL-1 alpha/IL-1A Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18 kDa and the accession number is P01582. | |||
TMPJ-00194 |
IL-20RB Protein, Human, Recombinant (hFc)
DIRS1,IL-20R-β,Interleukin-20 rec... |
Human | HEK293 Cells |
Interleukin-20 receptor subunit beta(IL20RB) is a single-pass type I membrane protein and belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains. There are two kinds of type II cytokine receptors : cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleukin-10 family (interleukin-10, interleukin-20 and interleukin-22). Type II cytokine receptors are similar to type I cytokine receptors except they do no... | |||
TMPY-05559 |
IL-20RB Protein, Human, Recombinant (His)
interleukin 20 receptor β,interleukin 20 receptor b... |
Human | Baculovirus Insect Cells |
IL-20RB Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 23.9 kDa and the accession number is Q6UXL0-1. | |||
TMPY-06662 |
IL-12RB1 Protein, Human, Recombinant
CD212,IMD30,interleukin 12 receptor, beta ... |
Human | HEK293 Cells |
IL-12RB1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 57.11 kDa and the accession number is NP_005526.1. | |||
TMPJ-00162 |
IL-1 alpha/IL-1A Protein, Human, Recombinant (hFc)
Hematopoietin-1,Interleukin-1 Alpha,白介素, |
Human | HEK293 Cells |
IL-1 alpha/IL-1A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 54 KDa and the accession number is P01583. | |||
TMPY-02817 |
IL-1F8 Protein, Human, Recombinant (His)
FIL1,FIL1H,IL |
Human | E. coli |
IL-1F8 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 19.3 kDa and the accession number is Q9NZH7-2. | |||
TMPY-00850 |
ST2/IL-1 RL1 Protein, Human, Recombinant
ST2,IL1RL1,ST2L,IL33R,T<... |
Human | HEK293 Cells |
ST2/IL-1 RL1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 35.6 kDa and the accession number is Q01638-2. | |||
TMPY-04096 |
ST2/IL-1 RL1 Protein, Mouse, Recombinant (His)
Ly84,St2-rs1,T1,ST2L,T1/ST2,Fit-<... |
Mouse | HEK293 Cells |
ST2/IL-1 RL1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is P14719-1. | |||
TMPY-02458 |
IL-1F8 Protein, Human, Recombinant
FILI-(ETA),FIL1-(ETA),IL... |
Human | E. coli |
IL-1F8 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.7 kDa and the accession number is Q9NZH7-2. | |||
TMPY-06981 |
IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli)
interleukin 1 α,IL1,白介素,IL |
Human | E. coli |
IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophage... | |||
TMPY-01359 |
ST2/IL-1 RL1 Protein, Human, Recombinant (His)
IL1RL1,IL‑1 R4,... |
Human | HEK293 Cells |
ST2/IL-1 RL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is Q01638-2. | |||
TMPY-00849 |
ST2/IL-1 RL1 Protein, Human, Recombinant (hFc)
ST2V,FIT-1,DER4,interleukin 1 receptor-lik... |
Human | HEK293 Cells |
ST2/IL-1 RL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.72 kDa and the accession number is Q01638-2. | |||
TMPJ-00981 |
PTX3 Protein, Mouse, Recombinant (His)
alpha-induced protein 5,pentraxin 3, long,pentaxin-related g... |
Mouse | HEK293 Cells |
Pentraxin-related protein PTX3, also known as Tumor necrosis factor-inducible gene 14 protein (TSG-14), belongs to the pentraxin family. PTX3 plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility. It’s subunit is a disulfide-linked homooctamer that binds to C1q. PTX3 concentration is elevated in the joint fluid of patients with rheumatoid arthritis (RA), indicating that PTX3 may be a potential mediator... | |||
TMPJ-00850 |
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)
Protein T1,suppression of tumorigenicity 2,Ly84,DER... |
Mouse | HEK293 Cells |
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-70 KDa and the accession number is P14719-2. | |||
TMPK-00638 |
IL-1 Rrp2/IL-1 R6 Protein, Cynomolgus, Recombinant (His)
IL1RL2,IL-1 Rrp2,IL<... |
Cynomolgus | HEK293 Cells |
IL-1 Rrp2/IL-1 R6 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 37.1 kDa and the accession number is G8F338. | |||
TMPK-00333 |
IL-1 Rrp2/IL-1 R6 Protein, Human, Recombinant (His & Avi), Biotinylated
IL-1 Rrp2,IL-1 R6,IL... |
Human | HEK293 Cells |
IL-1 Rrp2/IL-1 R6 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 39.1 kDa and the accession number is Q9HB29-1. | |||
TMPJ-00344 |
IL-18RAP Protein, Human, Recombinant (hFc & His)
IL-1R accessory protein-like,Interleukin-<... |
Human | HEK293 Cells |
IL-18RAP is a single-pass type I membrane protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 and IL18RAP is required for the activation of NF-kappa B and JNK in response to IL-18.Defects in IL18RAP are associated with Coeliac disease. | |||
TMPK-00332 |
IL-1 Rrp2/IL-1 R6 Protein, Human, Recombinant (His & Avi)
IL1RL2,IL-1 R6,IL |
Human | HEK293 Cells |
IL-1 Rrp2/IL-1 R6 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 39.1 kDa and the accession number is Q9HB29-1. | |||
TMPH-03497 |
IL-1 beta Protein, Sheep, Recombinant (His)
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Sheep | P. pastoris (Yeast) |
IL-1 beta Protein, Sheep, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 19.7 kDa and the accession number is P21621. | |||
TMPH-03743 |
IL-1 beta Protein, Zebrafish, Recombinant (His)
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Danio rerio (Zebrafish) | E. coli |
IL-1 beta Protein, Zebrafish, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 29.9 kDa and the accession number is E6N152. | |||
TMPH-03744 |
IL-1 beta Protein, Zebrafish, Recombinant (His & Myc)
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Danio rerio (Zebrafish) | E. coli |
IL-1 beta Protein, Zebrafish, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 32.9 kDa and the accession number is E6N152. | |||
TMPY-05836 |
IL-1 alpha/IL-1A Protein, Rat, Recombinant
interleukin 1, alpha,IL-1 α/I... |
Rat | E. coli |
IL-1 alpha/IL-1A Protein, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.80 kDa and the accession number is P16598. | |||
TMPY-00851 |
IL-1 R9 Protein, Human, Recombinant (hFc)
IL-1R9,interleukin 1 receptor acc... |
Human | HEK293 Cells |
IL-1 R9 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66 kDa and the accession number is Q9NP60. | |||
TMPY-01740 |
IL-1 R9 Protein, Human, Recombinant (His)
IL-1R9,IL1RAPL-2,IL<... |
Human | HEK293 Cells |
IL-1 R9 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.7 kDa and the accession number is Q9NP60. | |||
TMPK-00920 |
IL-1 alpha/IL-1A Protein, Cynomolgus, Recombinant (His)
IL-1A,白介素,IL-1 alpha,Int... |
Cynomolgus | HEK293 Cells |
The interleukin (IL)-1 family of cytokines is currently comprised of 11 members that have pleiotropic functions in inflammation and cancer. IL-1α and IL-1β were the first members of the IL-1 family to be described, and both signal via the same receptor, IL-1R. Over the last decade, much progress has been made in our understanding of biogenesis of IL-1β and its functions in human diseases. | |||
TMPH-03496 |
IL-1 beta Protein, Sheep, Recombinant (E. coli, His)
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Sheep | E. coli |
IL-1 beta Protein, Sheep, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 21.7 kDa and the accession number is P21621. | |||
TMPJ-00161 |
IL-1 alpha/IL-1A Protein, Human, Recombinant (Avi), Biotinylated
Hematopoietin-1,IL-1 α,IL |
Human | E. coli |
IL-1 alpha/IL-1A Protein, Human, Recombinant (Avi), Biotinylated is expressed in E. coli expression system with C-Avi tag. The predicted molecular weight is 19 KDa and the accession number is P01583. | |||
TMPH-02438 |
IL-1 alpha/IL1A Protein, Rhesus macaque, Recombinant (His & SUMO)
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Rhesus | E. coli |
Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. IL-1 alpha/IL1A Protein, Rhesus macaque, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag... | |||
TMPY-03493 |
ST2/IL-1 RL1 Protein, Mouse, Recombinant (hFc)
St2,ST2L,T1/ST2,interleukin 1 receptor-lik... |
Mouse | HEK293 Cells |
ST2/IL-1 RL1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.8 kDa and the accession number is P14719-1. | |||
TMPY-05452 |
ST2/IL-1 RL1 Protein, Cynomolgus, Recombinant (His)
interleukin 1 receptor-like 1 |
Cynomolgus | HEK293 Cells |
ST2/IL-1 RL1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.1 kDa and the accession number is XP_005575214.1. | |||
TMPY-02147 |
ST2/IL-1 RL1 Protein, Human, Recombinant (isoform a, His)
ST2L,FIT-1,IL‑1 R4,interleukin |
Human | HEK293 Cells |
ST2/IL-1 RL1 Protein, Human, Recombinant (isoform a, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.3 kDa and the accession number is Q01638-1. | |||
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